The largest non-nuclear weapon ever used in combat by the U.S. military, a bomb known officially as a GBU-43B, and nick-named the Mother of All Bombs, was dropped on an ISIS tunnel complex in Afghanistan yesterday. The 22,000-pound bomb was dropped from a U.S. Air Force C-130 transport, close to the Pakistani border. The bomb was developed during the Iraq war and tested at Eglin Air Force Base in 2003. There was no word on casualties or damage.